Search results for " Femoral"

showing 10 items of 30 documents

SNPs in bone-related miRNAs are associated with the osteoporotic phenotype

2017

AbstractBiogenesis and function of microRNAs can be influenced by genetic variants in the pri-miRNA sequences leading to phenotypic variability. This study aims to identify single nucleotide polymorphisms (SNPs) affecting the expression levels of bone-related mature microRNAs and thus, triggering an osteoporotic phenotype. An association analysis of SNPs located in pri-miRNA sequences with bone mineral density (BMD) was performed in the OSTEOMED2 cohort (n = 2183). Functional studies were performed for assessing the role of BMD-associated miRNAs in bone cells. Two SNPs, rs6430498 in the miR-3679 and rs12512664 in the miR-4274, were significantly associated with femoral neck BMD. Further, we…

0301 basic medicineconformation:Diseases::Wounds and Injuries::Fractures Bone::Hip Fractures [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Phenotype [Medical Subject Headings]Polimorfismo de nucleótido simpleGene ExpressionboneOsteoblastosDensidad ósea:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Cohort StudiesGene Frequencysingle nucleotide polymorphismBone DensityBone cellOssosgeneticsFracturas osteoporóticasCells CulturedGeneticsBone mineralMicroARNsMultidisciplinarymicroRNAbiologyQalleleR:Diseases::Wounds and Injuries::Fractures Bone::Osteoporotic Fractures [Medical Subject Headings]clinical trialMiddle Agedcohort analysisPhenotypeHumanosFenotipmedicine.anatomical_structureCancellous BoneosteoblastMedicine:Diseases::Musculoskeletal Diseases::Bone Diseases [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings]:Anatomy::Cells::Connective Tissue Cells::Osteoblasts [Medical Subject Headings]AlelosFenotipomusculoskeletal diseasesmedicine.medical_specialtyGenotypeScienceSingle-nucleotide polymorphismBiologychemistryPolymorphism Single NucleotideArticleBone and Bones:Anatomy::Musculoskeletal System::Skeleton::Bone and Bones::Cancellous Bone [Medical Subject Headings]03 medical and health sciencesCalcification PhysiologicInternal medicinemicroRNAmedicineHumanshumanproceduresAllele:Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles [Medical Subject Headings]AllelesFemoral neckGenetic associationAgedcell culture:Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Bone Density [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism Genetic::Polymorphism Single Nucleotide [Medical Subject Headings]OsteoblastsEnfermedades óseasFracturas de caderaComputational BiologyCuello femoral:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Antisense Elements (Genetics)::RNA Antisense::MicroRNAs [Medical Subject Headings]MicroRNAs030104 developmental biologyEndocrinologymulticenter studybone mineralizationNucleic Acid ConformationOsteoporosispathology:Anatomy::Musculoskeletal System::Skeleton::Bone and Bones::Bones of Lower Extremity::Leg Bones::Femur::Femur Neck [Medical Subject Headings]TranscriptomemetabolismGenotipoFractures
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Symptomatic Deep Femoral Artery Pseudoaneurysm Endovascular Exclusion. Case Report and Literature Review.

2017

Deep femoral artery pseudoaneurysms (DFAPs) are rare and generally occur after penetrating trauma or surgical procedures. A 36-year-old obese man presented with pain in correspondence of the anterior-lateral thigh after 6 months from gunshot wound. Duplex and computed tomography (CT) showed a bilobed right DFAP (maximal diameter 12.9 cm). The patient was managed urgently, under local anesthesia, by placement in the distal DFA of a Viabahn 8 × 100-mm stent graft (W L Gore & Associates, Inc). The postoperative course was uneventful, and the 24-month CT showed regular stent-graft patency and 20-mm DFAP shrinkage. The literature review reported 8 cases of DFAPs; of these 6 were managed by endo…

AdultMalemedicine.medical_specialtyComputed Tomography Angiographymedicine.medical_treatment030204 cardiovascular system & hematologySettore MED/22 - Chirurgia Vascolare030218 nuclear medicine & medical imaging03 medical and health sciencesPseudoaneurysmBlood Vessel Prosthesis Implantation0302 clinical medicineAneurysmBlood vessel prosthesisDeep Femoral ArteryMedicineVascular PatencyHumansVascular PatencyUltrasonography Doppler Duplexbusiness.industryEndovascular ProceduresStentGeneral Medicinemedicine.diseaseSurgeryBlood Vessel ProsthesisFemoral Arterysurgical procedures operativeTreatment OutcomeRegional Blood FlowSurgeryStentsWounds GunshotRadiologyGunshot woundbusinessCardiology and Cardiovascular MedicinePenetrating traumaAneurysm FalseAnnals of vascular surgery
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Polyvascular subclinical atherosclerosis in familial hypercholesterolemia: The role of cholesterol burden and gender

2019

International audience; BACKGROUND AND AIM:Heterozygous familial hypercholesterolemia (HeFH) is a genetic disease characterized by a heterogeneous phenotype. The assessment of cardiovascular (CV) risk is challenging for HeFH. Cholesterol burden (CB) allows to estimate the lifelong exposure to high levels of cholesterol. The aim of this study was to analyze the distribution of subclinical atherosclerosis and the relationship between atherosclerosis and the CB in a sample of HeFH patients, focusing on sex-related differences.METHODS AND RESULTS:154 asymptomatic HeFH subjects underwent coronary-artery-calcium score (CACs) and Doppler ultrasound of carotid and femoral arteries. Yearly lipid pro…

Carotid Artery DiseasesMaleCarotid atherosclerosisPeripheral arterial atherosclerosisTime Factors[SDV]Life Sciences [q-bio]Endocrinology Diabetes and MetabolismMedicine (miscellaneous)Coronary Artery DiseaseDiseaseFamilial hypercholesterolemia030204 cardiovascular system & hematologySeverity of Illness Indexchemistry.chemical_compound0302 clinical medicineRisk FactorsAtherosclerosis; Calcium score; Cardiovascular disease; Cardiovascular risk; Cholesterol burden; Coronary artery calcium; Familial hypercholesterolemia; Peripheral arterial atherosclerosis; Adult; Aged; Asymptomatic Diseases; Biomarkers; Carotid Artery Diseases; Cholesterol; Coronary Artery Disease; Cross-Sectional Studies; Female; Femoral Artery; Genetic Predisposition to Disease; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Paris; Peripheral Arterial Disease; Phenotype; Prevalence; Prognosis; Risk Assessment; Risk Factors; Severity of Illness Index; Sex Factors; Time Factors; Young AdultPrevalenceMedicineNutrition and Dietetics[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolismMiddle AgedPrognosisCardiovascular diseaseCalcium score3. Good healthFemoral ArteryCholesterol burdenCholesterolPhenotypeAtherosclerosiCardiologyPopulation studyFemalemedicine.symptomCardiology and Cardiovascular MedicineAdultParismedicine.medical_specialtyFamilial hypercholesterolemia030209 endocrinology & metabolismRisk AssessmentAsymptomaticCoronary artery calciumHigh cholesterolHyperlipoproteinemia Type IIPeripheral Arterial DiseaseYoung Adult03 medical and health sciencesSex Factors[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemInternal medicineHumansGenetic Predisposition to DiseaseAgedbusiness.industryCholesterolAtherosclerosismedicine.diseaseCardiovascular riskCross-Sectional StudieschemistrySubclinical atherosclerosisAsymptomatic DiseasesbusinessBiomarkers
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Mesothelial cyst of the round ligament of the uterus A case report of a rare condition

2021

Le cisti mesoteliali del legamento rotondo sono una rara causa di tumefazione inguinale nelle donne, la loro eziopatogenesi rimare poco chiara e i casi riportati in letteratura sono scarsi. Inoltre, quest’ultime sono raramente prese in considerazione nella diagnosi differenziale delle tumefazioni della regione inguinale nelle pazienti di sesso femminile, ragion per cui sono spesso identificate solo in corso di esplorazione chirurgica e correttamente diagnosticate solo dopo esame istopatologico. Una donna di 57 anni (BMI 37 kg / m2) si è presentato nel nostro dipartimento con una massa inguinale sinistra, con storia di 2 mesi, che causava disagio locale e peggioramento progressivo del dolore…

Diagnosis DifferentialCystsUterusHumansFemaleHernia InguinalMedical OveruseRound Ligament of UterusHernia FemoralMesothelial cyst Preoperative diagnosis Uterus
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Pool choice in a vertical landscape: tadpole rearing site flexibility in phytotelm-breeding frogs

2021

AbstractMany species of Neotropical frogs have evolved to deposit their tadpoles in small water bodies inside plant structures called phytotelmata. These pools are small enough to exclude large predators but have limited nutrients and high desiccation risk. Here, we explore phytotelm use by three common Neotropical species: Osteocephalus oophagus, an arboreal frog that periodically feeds eggs to its tadpoles; Dendrobates tinctorius, a tadpole-transporting poison frog with cannibalistic tadpoles; and Allobates femoralis, a terrestrial tadpole-transporting poison frog with omnivorous tadpoles. We found that D. tinctorius occupies pools across the chemical and vertical gradient, whereas A. fem…

Ecological nicheOsteocephalus oophagusArboreal locomotionbiologyDendrobatesNiche differentiationZoologyAllobates femoralisbiology.organism_classificationTadpolePredation
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Treatment of femoral pseudoaneurysm after vascular procedure. In: A multidisciplinary Approach to Cardiovascular Diseases

2016

IatrogenPseudoaneurysmfemoralPseudoaneurysm; femoral; IatrogenSettore MED/22 - Chirurgia Vascolare
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Localización exacta de la inserción femoral y medida de la distancia entre el punto de inserción femoral y patelar de la plastia de ligamento patelof…

2016

Introducción: La reconstrucción del ligamento patelofemoral medial (LPFM) es el procedimiento de elección en el tratamiento de los pacientes que sufren episodios de inestabilidad rotuliana lateral crónica. Sin embargo, se desconoce el punto exacto de fijación de la plastia del LPFM al fémur y los efectos en la clínica de una inserción femoral no anatómica. Objetivos: (1) Estudiar la biomecánica del injerto de LPFM reconstruido in vivo mediante imágenes 3D de Tomografía Computarizada (TC) a diferentes ángulos de flexión; (2) establecer la precisión de los métodos radiográficos de Schöttle y Stephen en la identificación del punto de fijación femoral de la plastia de LPFM tomando como referenc…

Inestabilidad rotuliana lateral crónicaTC 3DUNESCO::CIENCIAS MÉDICASReconstrucción anatómica:CIENCIAS MÉDICAS [UNESCO]Ligamento patelofemoral medialFijación femoral
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Less invasive (common) femoral artery aneurysm repair using endografts and limited dissection

2013

Objective We report our experience with the treatment of femoral artery aneurysms (FAAs) under local anaesthesia with limited dissection, using endografts to facilitate the proximal anastomosis and some distal anastomoses. Method Between January 2006 and December 2010, six males, mean age 72 years (range, 65–80 years) with FAAs were treated at the University Hospital of Zurich. All operations were performed under local anaesthesia with analgosedation, except for one performed under spinal anaesthesia. After limited dissection and puncture of the anterior wall of the FAA, a sheath and a self-expanding endograft were introduced over a guide wire and with fluoroscopy they were guided intralumi…

Malemedicine.medical_specialtyAnastomosismedicine.medical_treatmentEndograft610 Medicine & healthFemoral arteryDissection (medical)AnastomosisSettore MED/22 - Chirurgia Vascolare2705 Cardiology and Cardiovascular MedicineAneurysmmedicine.arteryDeep Femoral ArteryHumansMedicineAgedMedicine(all)Aged 80 and over10042 Clinic for Diagnostic and Interventional Radiologybusiness.industryEndovascular ProceduresBalloon catheterExternal iliac arteryStentmedicine.diseaseAneurysmBlood Vessel Prosthesis10020 Clinic for Cardiac Surgery2746 SurgerySurgeryFemoral ArteryCommon femoral arteryFemaleSurgeryRadiologyCardiology and Cardiovascular MedicinebusinessCommon femoral artery Aneurysm Endograft Anastomosis
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Effects of a Home-Based Physical Rehabilitation Program on Physical Disability After Hip Fracture: A Randomized Controlled Trial

2015

Abstract Objective Fewer than half of the patients with hip fracture will regain the prefracture level of physical functioning. This secondary analysis of a randomized controlled trial investigated the effects of a multicomponent home-based rehabilitation program (ProMo) on physical disability after hip fracture. Design Randomized, controlled, parallel-group trial. Setting Rehabilitation in participants' homes; measurements in university-based laboratory and local hospital. Participants Population-based clinical sample of community-dwelling people older than 60 years (n = 81) operated for hip fracture were randomized into intervention and control groups. Intervention The year-long intervent…

Malemedicine.medical_specialtyPhysical disabilityActivities of daily livingADLmedicine.medical_treatmentPopulationproximal femoral fractureWalkingRisk AssessmentGeelaw.inventionDisability EvaluationInjury Severity ScorePhysical medicine and rehabilitationRandomized controlled triallawActivities of Daily LivingmedicineHumansMobility LimitationeducationGeriatric AssessmentIADLPhysical Therapy ModalitiesGeneral NursingAgedAged 80 and overHip fractureeducation.field_of_studyRehabilitationHip Fracturesbusiness.industryHealth Policyta3141Recovery of FunctionGeneral MedicineMiddle Agedmedicine.diseaseHome Care ServicesPatient Outcome AssessmentTreatment OutcomeSample size determinationPhysical therapyFemaleGeriatrics and GerontologybusinessFollow-Up StudiesJournal of the American Medical Directors Association
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Fixation free femoral hernia repair with a 3D dynamic responsive implant. A case series report

2018

Abstract Background To date, no gold standard for the surgical treatment of femoral hernia exists. Pure tissue repair as well as mesh/plug implantation, open or laparoscopic, are the most performed methods. Nevertheless, all these techniques need sutures or mesh fixation. This implies the risk of damaging sensitive structures of the femoral area, along with complications related to tissue tear and postoperative discomfort consequent to poor quality mesh incorporation. The present retrospective multicenter case series highlights the results of femoral hernia repair procedures performed with a 3D dynamic responsive implant in a cohort of 32 patients during a mean follow up of 27 months. Mater…

Malemedicine.medical_specialtyPostoperative discomfortProstheses and Implantmedicine.medical_treatmentProsthesis ImplantationChronic pain030230 surgery3D dynamic prosthesiProsthesisFollow-Up StudieProsthesis ImplantationAbdominal wall03 medical and health sciencesFixation (surgical)0302 clinical medicineRetrospective StudiemedicineHumansHerniaHerniorrhaphyHernia repair complicationRetrospective StudiesSurgical repairPain Postoperativebusiness.industryHernia repair fixation freeProbiotic biologic responseProstheses and ImplantsGeneral MedicineMiddle AgedFemoral herniamedicine.diseaseHernia FemoralSurgeryTreatment Outcomemedicine.anatomical_structure030220 oncology & carcinogenesisFemaleSurgeryImplantbusinessHumanFollow-Up StudiesInternational Journal of Surgery
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